January, 2015

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Good lecturing is an art, and it takes real dedication


复旦将“代表性教学成果”纳入职称评价 青年教师吴燕华副教授提名获学术委员会高票通过 ©微复旦

Transcription factor interaction with COMPASS-like complex regulates histone H3K4 trimethylation


Accumulation of unfolded or misfolded proteins causes endoplasmic reticulum (ER) stress, which activates a set of ER membrane-associated transcription factors for protein homeostasis regulation. Previous genome-wide chromatin immunoprecipitation analysis shows a strong correlation between histone H3K4 trimethylation (H3K4me3) and active gene expression. However, how the histone modification com

TBX6 Null Variants and a Common Hypomorphic Allele in Congenital Scoliosis


BACKGROUND: Congenital scoliosis is a common type of vertebral malformation. Genetic susceptibility has been implicated in congenital scoliosis. METHODS: We evaluated 161 Han Chinese persons with sporadic congenital scoliosis, 166 Han Chinese controls, and 2 pedigrees, family members of which had a 16p11.2 deletion, using comparative genomic hybridization, quantitative polymerase-chain-reaction